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Description of Individual Course Units| Course Unit Code | Course Unit Title | Type of Course Unit | Year of Study | Semester | Number of ECTS Credits | | KTY132 | Plant Chemistry and Analysis Methods | Elective | 1 | 2 | 6 |
| | Level of Course Unit | | Second Cycle | | Objectives of the Course | | Examples of active and auxiliary substances in the structure of plants are the use of plants among the public, the introduction of chemical compounds of herbal origin for different purposes, pharmaceutical active substances (alternative medicine), flavor and fragrance, plants used in cosmetics, agriculture, livestock, herbal teas, aromatherapy, poisonous plants and narcotic plants. It is aimed to introduce by giving and to determine the necessary isolation and spectroscopic methods. In addition, it is aimed to explain the production of these herbal compounds in natural and synthetic ways under laboratory conditions by giving examples. | | Name of Lecturer(s) | | Prof.Dr.Ali Savaş BÜLBÜL | | Learning Outcomes | | 1 | The student who took the Plant Chemistry course will learn about the use of plants among the public, chemical compounds of herbal origin for various purposes, drug active substances (alternative medicine), flavor and fragrance, cosmetics, agriculture, plants used in livestock, herbal teas, aromatherapy, poisonous plants and narcotic plants. be able to determine the necessary isolation and spectroscopic methods for them by having knowledge about active and auxiliary substances. Can independently carry out a study that requires expertise on this subject. | | 2 | Can develop new strategic approaches for the solution of complex problems, use research methods and take responsibility to produce solutions. |
| | Mode of Delivery | | Normal Education | | Prerequisites and co-requisities | | NO | | Recommended Optional Programme Components | | NO | | Course Contents | | Identification of the chemical structure of the plant / plant analysis methods / classification of plants / medicinal, psychological, nutritional, dye, textile, fragrance, cosmetic components / inorganic elements / alkanes / fatty acids / essential oils / sugars / terpenes / alkaloids / phenolic compounds / enzyme / vitamin / antibiotic / tannin / resin and macromolecules | | Weekly Detailed Course Contents | |
| 1 | Biosynthesis definition | NO | NO | | 2 | Biosynthesis of primary and secondary metabolites | NO | NO | | 3 | Phytochemistry and biosynthesis | NO | NO | | 4 | Enzymatic activities in biosynthesis reactions | NO | NO | | 5 | Important biosynthesis and pathways in plants | NO | NO | | 6 | Primary Metabolites | NO | NO | | 7 | Carbohydrates, Lipids, Proteins, Enzymes, Nucleic acids | NO | NO | | 8 | Carbohydrates, Lipids, Proteins, Enzymes, Nucleic acids | NO | NO | | 9 | Secondary Metabolites | NO | NO | | 10 | Glycosides, Tannins, Alkaloids, Isoprenoids | NO | NO | | 11 | Glycosides, Tannins, Alkaloids, Isoprenoids | NO | NO | | 12 | Organoleptic, Microscopic and Microchemical Methods | NO | NO | | 13 | Organoleptic, Microscopic and Microchemical Methods | NO | NO | | 14 | Diagnostic Reactions of Herbal Substances | NO | NO |
| | Recommended or Required Reading | | Baytop, A., (1981), Anatomical Structure of Herbal Drugs, Istanbul University Publications No: 2828, Faculty of Pharmacy Publications No: 32, IstanbulBaytop, T. (1983). Pharmacognosy Textbook, Volume II, Istanbul Univ.Yay. No.2003, Istanbul.Baytop, T. (1986). Pharmacognosy Textbook, Volume I, Istanbul University. Arrow. no. 3399, Istanbul.Baytop, A. (1991). Anatomical Structure of Herbal Drugs, İstanbul: İstanbul Üniversitesi Yayınları.Baytop, A., (1993) Pharmaceutical Botanical Applications, İstanbul University Publication No: 3778, İstanbul.Baytop, A., (1996), Pharmaceutical Botany, İstanbul University Publication No: 3637 , Faculty of Pharmacy Publications No: 58, İstanbulBaser, KHC, Kırmızımer, N., (2009), Pharmacognosy I Applications Handbook, Anadolu University, Faculty of Pharmacy, Eskişehir.Bhat, SV (2005). Chemistry of Natural Products, Springer, Berlin. Bisset, N. G., (1994), Herbal Drugs and Phytopharmaceuticals, CRC Press, Boca Raton. Bu'Lock, J.D. (1965). The Biosynthesis of Natural Products, Mc Graw-Hill, London. Cane, D. E. (1999) Comprehensive Natural Products Chemistry, Vol. 1-9, Elsevier, Amsterdam.Ciulei, I., (1982), Practical Manuals on the Industrial Utilization of Medicinal and Aromatic Plants, I. Methodolgy for Analysis of Vegetable Drugs, UNIDO, Romania Pub., Bucharest.Cakirlar, H. , Doğan, C. and Özmen E. (2009) Annotated General Atlas of Botany and Plant Anatomy, p. 26, 30, Palme Publishing. Celebioglu, S. (1949). Pharmacognosy. Istanbul: Istanbul University Press. Davis, P.H., (1965-1985), Flora of Turkey and East Aegean Islands, Vol. 1-9, Edinburgh University Press, Edinburgh. Davis, P.H., Mill, R.R., Kit Tan, (1988), Flora of Turkey and East Aegean Islands, Vol. 10, Edinburgh University Press, Edinburgh.Dewick, M.P. (2002). The Biosynthesis of C5-C25 Terpenoid Compounds, Nat. prod. Rep., 19, 181-222. Dewick, P.M. (2009). Medicinal Natural Products, A Biosynthetic Approach, 3rd Edition, John Wiley & Sons;, Chichester. Dey, P.M., and Harborne, J.B. (1998). Methods in Plant Biochemistry, Vol. 1-7, Academic Press. Evans, W.C.,(2009). Trease and Evans' Pharmacognosy, 16th ed., WB Saunders, Edinburgh. Gissman, T.A., and Crout, D.H. G. (1969). Organic Chemistry of Secondary Plant Metabolism, Freeman, Cooper Company, USA.Güner, A., Özhatay, N., Ekim, T., Başer, K.H.C., (2000), Flora of Turkey and East Aegean Islands, Vol. 11, Edinburgh University Press, Edinburgh. Hansel R., and Sticher O. (2007) Pharmakognosie – Phytopharmazie, Springer-Lehrbuch, München. Hanson J.R. (2003) Natural Products: the Secondary Metabolites (Tutorial Chemistry Texts), Royal Society of Chemistry, London.Harborne, J.B. (1984). Phytochemical Methods, (2nd ed.), London: Chapman and Hall, Manitto, P. (1981). Biosynthesis of Natural Products, Ellis Horwood, London. Ross, M.S.F., Brain, K.R. (1977). An Introduction to Phytopharmacy. London: Pitman Medical. Samuelson, G., (2004). Drugs of Natural Origin, A Textbook of Pharmacognosy, 5th Edition, Swedish Pharmaceutical Press, Sweden.T.C. Ministry of Health, General Directorate of Pharmaceuticals and Pharmacy (2004). Turkish Pharmacopoeia (Adaptation of European Pharmacopoeia). Ankara: Gökçe Ofset Ltd. Sti. Torssell, K.B.G. (1997). Natural Product Chemistry, Apotekarsocieten, Swedish Pharmaceutical Society, Sweden.Tyleri, V.E., Brady, L.R., Robbers, J.E. (1988), Pharmacognosy, USA, PA, Lea & Febiger; Wallis, T. E., (1967), Textbook of Pharmacognosy, Fifth Ed., J. & A. Churchill Ltd. london | | Planned Learning Activities and Teaching Methods | | | Assessment Methods and Criteria | |
| Midterm Examination | 1 | 100 | | SUM | 100 | |
| Final Examination | 1 | 100 | | SUM | 100 | | Term (or Year) Learning Activities | 40 | | End Of Term (or Year) Learning Activities | 60 | | SUM | 100 |
| | Language of Instruction | | | Work Placement(s) | | NO |
| | Workload Calculation | |
| Midterm Examination | 1 | 2 | 2 | | Final Examination | 1 | 2 | 2 | | Writing Paper | 8 | 15 | 120 | | Criticising Paper | 2 | 5 | 10 | | Self Study | 1 | 20 | 20 | | Individual Study for Mid term Examination | 2 | 15 | 30 | | Individual Study for Final Examination | 1 | 5 | 5 | |
| Contribution of Learning Outcomes to Programme Outcomes | | LO1 | 4 | 4 | 4 | 5 | 4 | 5 | 5 | 5 | 5 | 5 | 4 | 4 | 4 | 4 | 4 | 4 | 5 | | LO2 | 4 | 4 | 4 | 5 | 4 | 4 | 4 | 4 | 5 | 4 | 4 | 5 | 5 | 5 | 5 | 5 | 4 |
| | * Contribution Level : 1 Very low 2 Low 3 Medium 4 High 5 Very High |
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