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Description of Individual Course Units| Course Unit Code | Course Unit Title | Type of Course Unit | Year of Study | Semester | Number of ECTS Credits | | KTY117 | Plant Chemistry and Analysis Methods | Elective | 1 | 1 | 6 |
| | Level of Course Unit | | Second Cycle | | Objectives of the Course | | The use of plants among the people, the introduction of chemical compounds of plant origin for various purposes, Decontamination of drugs
active ingredients (alternative medicine), flavoring and olfactory, cosmetics, agriculture, plants used in animal husbandry,
active and auxiliary substances in the structures of herbal teas, aromatherapy, poisonous plants and narcotic plants
it is aimed to introduce by giving examples and to determine the necessary isolation and spectroscopic methods.
In addition, by giving examples of the synthetic production of these vegetable compounds under natural and laboratory conditions
it is aimed to explain | | Name of Lecturer(s) | | Prof.Dr.Ali Savaş BÜLBÜL | | Learning Outcomes | | 1 | Will be able to interpret biosynthesis in plants. | | 2 | Explain primary and secondary metabolites. | | 3 | Will be able to compare Organoleptic, Microscopic and Microchimic Methods. | | 4 | Will be able to apply Diagnostic Reactions of Plant Substances. |
| | Mode of Delivery | | Normal Education | | Prerequisites and co-requisities | | NOT | | Recommended Optional Programme Components | | NOT | | Course Contents | | Identification of the chemical structure of the plant / methods of plant analysis / classification of plants / medical,
psychological, nutritional, dye, textile, fragrance, cosmetic components / inorganic elements / alkanes / oil
acids / essential oils / sugars / terpenes / alkaloids / phenolic compounds / enzyme / vitamin / antibiotic /
tannin / resin and macromolecules | | Weekly Detailed Course Contents | |
| 1 | Definition of biosynthesis, Biosynthesis of primary and secondary metabolites | | | | 2 | Phytochemistry and biosynthesis | | | | 3 | Enzymatic activities in biosynthesis reactions | | | | 4 | | | | | 5 | Primary Metabolites | | | | 6 | Carbohydrates, Lipids, Proteins, Enzymes, Nucleic acids | | | | 7 | Midterm | | | | 8 | Carbohydrates, Lipids, Proteins, Enzymes, Nucleic acids | | | | 9 | Glycosides, Tannins, Alkaloids, Isoprenoids | | | | 10 | Glycosides, Tannins, Alkaloids, Isoprenoids | | | | 11 | Glycosides, Tannins, Alkaloids, Isoprenoids | | | | 12 | Organoleptic, Microscopic and Microchemical Methods | | | | 13 | Organoleptic, Microscopic and Microchemical Methods | | | | 14 | Organoleptic, Microscopic and Microchemical Methods | | | | 15 | Final exam | | |
| | Recommended or Required Reading | | Baytop, A., (1981), Bitkisel Drogların Anatomik Yapısı, İstanbul Üniversitesi Yayınları No: 2828, Eczacılık Fakültesi Yayınları No: 32, İstanbulBaytop, T. (1983). Farmakognozi Ders Kitabı, Cilt II, İstanbul Üniv.Yay. No.2003, İstanbul.Baytop, T. (1986). Farmakognozi Ders Kitabı, Cilt I, İstanbul Üniv. Yay. No. 3399, İstanbul.Baytop, A. (1991). Bitkisel Drogların Anatomik Yapısı, İstanbul: İstanbul Üniversitesi Yayınları.Baytop, A., (1993) Farmasötik Botanik Uygulamaları, İstanbul Üniversitesi Yayın No: 3778, İstanbul.Baytop, A., (1996), Farmasötik Botanik, İstanbul Üniversitesi Yayınları No: 3637, Eczacılık Fakültesi Yayınları No: 58, İstanbulBaşer, K. H. C., Kırımer, N., (2009), Farmakognozi I Uygulamaları El Kitabı, Anadolu Üniversite, Eczacılık Fakültesi, Eskişehir.Bhat, S.V. (2005). Chemistry of Natural Products, Springer, Berlin. Bisset, N. G., (1994), Herbal Drugs and Phytopharmaceuticals, CRC Press, Boca Raton.Bu’Lock, J.D. (1965). The Biosynthesis of Natural Products, Mc Graw-Hill, London.Cane, D. E. (1999) Comprehensive Natural Products Chemistry, Vol. 1-9, Elsevier, Amsterdam.Ciulei, I., (1982), Practical Manuals on the Industrial Utilization of Medicinal and Aromatic Plants, I. Methodolgy for Analysis of Vegetable Drugs, UNIDO, Romania Pub., Bucharest.Çakırlar, H., Doğan, C. ve Özmen E. (2009) Açıklamalı Genel Botanik ve Bitki Anatomisi Atlası, s. 26, 30, Palme Yayıncılık.Çelebioğlu, S. (1949). Farmakognozi. İstanbul : İstanbul Üniversitesi Yayınları.Davis, P.H., (1965-1985), Flora of Turkey and East Aegean Islands, Vol. 1-9, Edinburgh University Press, Edinburgh.Davis, P.H., Mill, R.R., Kit Tan, (1988), Flora of Turkey and East Aegean Islands, Vol. 10, Edinburgh University Press, Edinburgh.Dewick, M.P. (2002). The Biosynthesis of C5-C25 Terpenoid Compounds, Nat. Prod. Rep., 19, 181-222. Dewick, P.M. (2009). Medicinal Natural Products, A Biosynthetic Approach, 3rd Edition, John Wiley &Sons;, Chichester.Dey, P.M.,ve Harborne, J.B. (1998). Methods in Plant Biochemistry, Vol. 1-7, Academic Press.Evans, W.C.,(2009). Trease and Evans’ Pharmacognosy, 16th ed., WB Saunders, Edinburgh.Gissman, T.A., ve Crout, D.H G. (1969). Organic Chemistry of Secondary Plant Metabolism, Freeman, Cooper Company, USA.Güner, A., Özhatay, N., Ekim, T., Başer, K.H.C., (2000), Flora of Turkey and East Aegean Islands, Vol. 11, Edinburgh University Press, Edinburgh.Hänsel R., ve Sticher O. (2007) Pharmakognosie – Phytopharmazie, Springer-Lehrbuch, München. Hanson J.R. (2003) Natural Products: the Secondary Metabolites (Tutorial Chemistry Texts), Royal Society of Chemistry, London.Harborne, J.B. (1984). Phytochemical Methods, (2. bs), London: Chapman and Hall,Manitto, P. (1981). Biosynthesis of Natural Products, Ellis Horwood, London.Ross, M.S.F., Brain, K.R. (1977). An Introduction to Phytopharmacy. London: Pitman Medical.Samuelson, G., (2004). Drugs of Natural Origin, A Textbook of Pharmacognosy, 5th Edition, Swedish Pharmaceutical Pres, Sweden.T.C. Sağlık Bakanlığı İlaç ve Eczacılık Genel Müdürlüğü (2004). Türk Farmakopesi (Avrupa Farmakopesi Adaptasyonu). Ankara: Gökçe Ofset Ltd. Şti.Torssell, K.B.G. (1997). Natural Product Chemistry, Apotekarsocieten, Swedish Pharmaceutical Society, Sweden.Tyleri, V.E., Brady, L.R., Robbers, J.E. (1988), Pharmacognosy, USA, PA, Lea&Febiger;.Wallis, T. E., (1967), Textbook of Pharmacognosy, Fifth Ed., J. & A. Churchill Ltd. London. | | Planned Learning Activities and Teaching Methods | | | Assessment Methods and Criteria | |
| Midterm Examination | 1 | 100 | | SUM | 100 | |
| Final Examination | 1 | 100 | | SUM | 100 | | Term (or Year) Learning Activities | 30 | | End Of Term (or Year) Learning Activities | 70 | | SUM | 100 |
| | Language of Instruction | | Turkish | | Work Placement(s) | | NOT |
| | Workload Calculation | |
| Midterm Examination | 30 | 1 | 30 | | Final Examination | 70 | 1 | 70 | | Writing Paper | 20 | 2 | 40 | | Criticising Paper | 20 | 2 | 40 | |
| Contribution of Learning Outcomes to Programme Outcomes | | LO1 | 4 | 5 | 3 | 4 | 4 | 5 | 4 | 3 | 3 | 4 | 4 | 4 | 4 | 4 | 4 | 3 | 4 | | LO2 | 5 | 4 | 4 | 4 | 4 | 4 | 4 | 4 | 4 | 4 | 3 | 5 | 4 | 3 | 3 | 4 | 4 | | LO3 | 5 | 4 | 4 | 5 | 3 | 4 | 4 | 4 | 4 | 3 | 4 | 4 | 3 | 4 | 4 | 4 | 4 | | LO4 | 4 | 5 | 4 | 4 | 5 | 4 | 3 | 4 | 3 | 4 | 4 | 4 | 4 | 4 | 4 | 4 | 4 |
| | * Contribution Level : 1 Very low 2 Low 3 Medium 4 High 5 Very High |
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