| Course Unit Code | Course Unit Title | Type of Course Unit | Year of Study | Semester | Number of ECTS Credits | | OT207 | Free Radicals and Antioxidants | Elective | 1 | 1 | 6 |
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| Level of Course Unit |
| Second Cycle |
| Objectives of the Course |
| It is aimed to analyze the chemical and biochemical substances of antioxidants and free radicals and to examine biocompatibility and critical functioning studies. |
| Name of Lecturer(s) |
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| Learning Outcomes |
| 1 | The student will have information about free radicals and antioxidants' chemical and biochemical properties. | | 2 | Students will have information about diseases caused by free radicals. | | 3 | The student gains knowledge about the mechanism of action of antioxidants. | | 4 | The student will have the basic knowledge for developing technologies to be used in the prevention, diagnosis, and treatment of diseases caused by free radicals. |
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| Mode of Delivery |
| Normal Education |
| Prerequisites and co-requisities |
| None |
| Recommended Optional Programme Components |
| None |
| Course Contents |
| How are free radicals produced? The effects of free radicals on biological molecules and the relationship between these free radicals and disease development are analyzed, as well as the properties of antioxidants, natural and artificial antioxidants, the mechanism of action of antioxidants, and the antioxidant defense system. |
| Weekly Detailed Course Contents |
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| 1 | Reactive oxygen species and formation | | | | 2 | Oxygen radicals | | | | 3 | Superoxide, hydrogen peroxide, hydroxyl radical and singlet oxygen radicals | | | | 4 | Sources of free radicals | | | | 5 | Transition metals and free radicals | | | | 6 | Free radical formation by phagocytosis and respiratory burst | | | | 7 | Effects of free radicals on biomolecules | | | | 8 | | Midterm Exam | | | 9 | Antioxidant defense system | | | | 10 | Endogenous antioxidants | | | | 11 | Exogenous antioxidants | | | | 12 | Mechanisms of action of antioxidants | | | | 13 | Non-enzymatic antioxidants | | | | 14 | Enzymatic antioxidants | | | | 15 | Final exam | | |
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| Recommended or Required Reading |
| Oxidants, Antioxidants And Free Radicals, Steven Baskin (Editor), Harry Salem (Editor), Taylor&Francis Publisher |
| Planned Learning Activities and Teaching Methods |
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| Assessment Methods and Criteria | |
| Midterm Examination | 1 | 60 | | Quiz | 2 | 20 | | Report Presentation | 4 | 20 | | SUM | 100 | |
| Final Examination | 1 | 60 | | Quiz | 4 | 20 | | Individual Study for Final Examination | 2 | 20 | | SUM | 100 | | Term (or Year) Learning Activities | 60 | | End Of Term (or Year) Learning Activities | 40 | | SUM | 100 |
| | Language of Instruction | | | Work Placement(s) | | None |
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| Workload Calculation |
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| Midterm Examination | 1 | 2 | 2 |
| Final Examination | 1 | 2 | 2 |
| Attending Lectures | 12 | 10 | 120 |
| Report Presentation | 8 | 7 | 56 |
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| Contribution of Learning Outcomes to Programme Outcomes |
| LO1 | 4 | | | | | | | 5 | | | | 4 | | | | 3 | | | 5 | | | 5 | | | | LO2 | 5 | | | | | | | 4 | | | | 5 | | | | 4 | | | 4 | | | 4 | | | | LO3 | 4 | | | | | | | 5 | | | | 4 | | | | 4 | | | 5 | | | 3 | | | | LO4 | 3 | | | | | | | 4 | | | | 5 | | | | 3 | | | 4 | | | 5 | | |
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| * Contribution Level : 1 Very low 2 Low 3 Medium 4 High 5 Very High |
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