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Description of Individual Course Units| Course Unit Code | Course Unit Title | Type of Course Unit | Year of Study | Semester | Number of ECTS Credits | | BD112B | Medical Biology and Genetics | Compulsory | 1 | 2 | 4 |
| | Level of Course Unit | | First Cycle | | Objectives of the Course | | The students will learn about the structure of the cell, organelles and the relations between the cells, the structural features of genetic material and replication mechanism, genetic code and genetic control mechanisms for the cell, types and characteristics of human inheritance patterns, characteristics and prevalence of changes in genetic material, the importance of genetics in nutritional disorders and in the formation of biotechnological products. | | Name of Lecturer(s) | | Dr.Öğr. Üyesi Filiz AYGÜN ERTÜRK | | Learning Outcomes | | 1 | Understand the structure of the cell, its organelles, and the relationships of the cells with each other. | | 2 | Learn the structural properties and replication mechanism of genetic material. | | 3 | Genetic code and genetic control mechanisms to understand the importance of the cell. | | 4 | Learn the types and characteristics of human inheritance models. | | 5 | Understand the importance of genetics in nutritional disorders and in the creation of biotechnological products. |
| | Mode of Delivery | | Second Education | | Prerequisites and co-requisities | | None | | Recommended Optional Programme Components | | None | | Course Contents | | Living organisms, biomolecules, cell structure and function, energy metabolism, the nature of the genetic material, DNA packaging and chromosome structure, RNA structure, function and synthesis, genetic code and protein synthesis, basic principles of inheritance, single gene disorders with Mendelian inheritance patterns, cell cycle and cell division, mutation,
genetics in malnutrition and generation of biotechnological products. | | Weekly Detailed Course Contents | |
| 1 | Introduction to medical biology, historical approach, cell general characteristics, cell examination methods | | | | 2 | Cell organization (prokaryote-eukaryote comparison), cell membrane and properties | | | | 3 | Cell structure and functions
| | | | 4 | Energy metabolism
| | | | 5 | The nature and function of genetic material, regulation of DNA-RNA, gene organization and gene expression | | | | 6 | DNA packaging and chromosome structure, cell cycle and DNA replication, transcription and translation | | | | 7 | RNA structure, synthesis and function | | | | 8 | MIDTERM EXAM | | | | 9 | Genetic code and protein synthesis, chromosomal structure and number anomalies, mutation and polymorphism | | | | 10 | DNA repair and repair mechanisms, cell aging, apoptosis and cancer mechanisms | | | | 11 | Mendel's inheritance in the basic principles of inheritance and in human single gene disorders | | | | 12 | Cell cycle and cell division | | | | 13 | Mutation, nutrition-related genes and biotechnological products | | | | 14 | Molecular biology techniques, genetics of inherited metabolic diseases
| | | | 15 | Genetic Diagnosis and Counseling | | |
| | Recommended or Required Reading | | • Prof. Dr. Halil Kasap, Tıbbi Biyoloji ve Genetik, Akademisyen Kitabevi, Ankara 2021.
• Prof. Dr. Hasan Veysi Güneş, Moleküler Hücre Biyolojisi, İstanbul Tıp Kitabevi, 3. Baskı, 2013.
• Bruce Alberts, Dennis Bray, Karen Hopkin, Alexander D Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter
• Walter. Essential Cell Biology, Fourth Edition, Garland Science Publishers, USA, 2013.
• Robert L. Nussbaum, Roderick R. Mcinnes, Huntington F. Willard. Thompson and Thompson Tıbbi Genetik, Güneş tıp Kitabevi, 2005.
• Başaran Ayşe. Tıbbi Biyoloji Ders kitabı. Pelikan Yayıncılık Ltd. Şti.,2009. | | Planned Learning Activities and Teaching Methods | | | Assessment Methods and Criteria | |
| Midterm Examination | 1 | 100 | | SUM | 100 | |
| Final Examination | 1 | 100 | | SUM | 100 | | Term (or Year) Learning Activities | 40 | | End Of Term (or Year) Learning Activities | 60 | | SUM | 100 |
| | Language of Instruction | | Turkish | | Work Placement(s) | | None |
| | Workload Calculation | |
| Midterm Examination | 1 | 1 | 1 | | Final Examination | 1 | 2 | 2 | | Attending Lectures | 14 | 2 | 28 | | Question-Answer | 14 | 1 | 14 | | Self Study | 14 | 2 | 28 | | Individual Study for Mid term Examination | 7 | 3 | 21 | | Individual Study for Final Examination | 7 | 3 | 21 | |
| Contribution of Learning Outcomes to Programme Outcomes | | LO1 | 5 | 4 | 2 | 4 | 4 | 2 | 2 | 1 | 4 | 2 | 1 | 4 | 3 | 4 | 2 | | LO2 | 5 | 4 | 2 | 4 | 4 | 2 | 2 | 1 | 4 | 2 | 1 | 4 | 3 | 4 | 2 | | LO3 | 5 | 4 | 2 | 4 | 4 | 2 | 2 | 1 | 4 | 2 | 1 | 4 | 3 | 4 | 2 | | LO4 | 5 | 4 | 2 | 4 | 4 | 2 | 2 | 1 | 4 | 2 | 1 | 4 | 3 | 4 | 2 | | LO5 | 5 | 4 | 2 | 4 | 4 | 2 | 2 | 1 | 4 | 3 | 1 | 4 | 5 | 5 | 5 |
| | * Contribution Level : 1 Very low 2 Low 3 Medium 4 High 5 Very High |
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